Defects in the necroptosis machinery are a cancer resistance mechanism to checkpoint inhibitor immunotherapy

Date Published

August 27, 2025

Sax A, May P, Enssle S, Soliman N, Nedelko T, Mandracci G, Stogbauer F, Joachim L, Winter C, Bassermann F, Steiger K, El Khawanky N, Poeck H, Heidegger S. Defects in the necroptosis machinery are a cancer resistance mechanism to checkpoint inhibitor immunotherapy. J Immunother Cancer. 2025 May 8. 13doi:10.1136/jitc-2024-010433. PMID: 40345706