Publications
Research at the Leibniz Institute for Immunology focuses on the development of pioneering immune-cell therapies targeting cancer, autoimmune diseases, and chronic inflammation. While developments in this field are highly relevant within the medical community, they are also of great interest to the wider general public. The LIT has a comprehensive archive of international articles, publications, lectures, and online resources aimed at a variety of audiences. So, whoever you are, if you do not find what you are looking for, please do not hesitate to contact us.
Xu JJ, Scoca V, Chen Y, Zhan YA, Fisher A, Udoh EO, Fernando S, Alija B, Pantazi J, Sudunagunta V, Stewart E, Galang AMD, Williams M, Bhagat G, Gebhard C, Visconte V, Ondrejka S, Delwel R, Hu M, Koche R, Viny AD. Enhanced FLI1 accessibility mediates STAG2-mutant leukemogenesis. bioRxiv. 2025 Apr 3. doi:10.1101/2025.04.01.646632. PMID: 40236115
Schmidleithner L, Stuve P, Feuerer M. Transposable elements as instructors of the immune system. Nat Rev Immunol. 2025 Apr 29. doi:10.1038/s41577-025-01172-3. PMID: 40301669
Abken H. CAR T cell therapies in gastrointestinal cancers: current clinical trials and strategies to overcome challenges. Nat Rev Gastroenterol Hepatol. 2025 Apr 14. doi:10.1038/s41575-025-01062-y. PMID: 40229574
Cormican JA, Medfai L, Wawrzyniuk M, Pasen M, Afrache H, Fourny C, Khan S, Gneisse P, Soh WT, Timelli A, Nolfi E, Pannekoek Y, Cope A, Urlaub H, Sijts A, Mishto M, Liepe J. PEPSeek-Mediated Identification of Novel Epitopes From Viral and Bacterial Pathogens and the Impact on Host Cell Immunopeptidomes. Mol Cell Proteomics. 2025 Apr. 24:100937. doi:10.1016/j.mcpro.2025.100937. PMID: 40044041
Heidenreich S, Egger-Heidrich K, Halter JP, Jost L, Stolzel F, Perl M, Denk A, Edinger M, Herr W, Kroger N, Wolff D, Ayuk F, Fante MA. Safety and efficacy of the ROCK-2-inhibitor Belumosudil in cGvHD treatment – a retrospective, German-Swiss multicenter real-world data analysis. Bone Marrow Transplant. 2025 Apr. 60:439-446. doi:10.1038/s41409-024-02507-9. PMID: 39809902
Stuve P, Godoy GJ, Ferreyra FN, Hellriegel F, Boukhallouk F, Kao YS, More TH, Matthies AM, Akimova T, Abraham WR, Kaever V, Schmitz I, Hiller K, Lochner M, Salomon BL, Beier UH, Rehli M, Sparwasser T, Berod L. ACC1 is a dual metabolic-epigenetic regulator of Treg stability and immune tolerance. Mol Metab. 2025 Apr. 94:102111. doi:10.1016/j.molmet.2025.102111. PMID: 39929287
Weich L, Brummer C, Ghimire S, Peter K, Althammer M, Babl N, Voll F, Bruss C, Hoering M, Wallner S, Siska PJ, Holler E, Herr W, Bruns H, Heid IM, Stark K, Kreutz M, Matos C. Impact of Liver and Kidney Function on Vitamin D3 Metabolism in Female and Male Patients Undergoing Allogeneic Hematopoietic Stem-Cell Transplantation. Int J Mol Sci. 2025 Mar 21. 26doi:10.3390/ijms26072866. PMID: 40243448
Knelangen N, Bader U, Maniaki E, Langan PS, Engert F, Drees B, Schwarzer J, Kotter B, Kiefer L, Gattinoni L, Engels B, Mittelstaet J, Webster B. CAR T cells re-directed by a rationally designed human peptide tag demonstrate efficacy in preclinical models. Cytotherapy. 2025 Mar 25. doi:10.1016/j.jcyt.2025.03.506. PMID: 40257412
Ewendt F, Drewitz F, Althammer M, Eichler C, Brandsch C, Brey S, Winkler TH, Wilkens MR, St-Arnaud R, Kreutz M, Stangl GI. Vitamin D stimulates Il-15 synthesis in rodent muscle. Biochem Biophys Rep. 2025 Mar. 41:101925. doi:10.1016/j.bbrep.2025.101925. PMID: 40134939
Sollier E, Riedel A, Toprak UH, Wierzbinska JA, Weichenhan D, Schmid JP, Hakobyan M, Touzart A, Jahn E, Vick B, Brown-Burke F, Kelly K, Kelekci S, Pejkovska A, Goyal A, Bahr M, Breuer K, Chen MM, Llamazares-Prada M, Hartmann M, Schonung M, Correia N, Trumpp A, Abdullah Y, Klingmuller U et al. Enhancer hijacking discovery in acute myeloid leukemia by pyjacker identifies MNX1 activation via deletion 7q. Blood Cancer Discov. 2025 Mar 31. doi:10.1158/2643-3230.BCD-24-0278. PMID: 40162972