Publications
Research at the Leibniz Institute for Immunology focuses on the development of pioneering immune-cell therapies targeting cancer, autoimmune diseases, and chronic inflammation. While developments in this field are highly relevant within the medical community, they are also of great interest to the wider general public. The LIT has a comprehensive archive of international articles, publications, lectures, and online resources aimed at a variety of audiences. So, whoever you are, if you do not find what you are looking for, please do not hesitate to contact us.
Kolb S, Diekmann L, Lochert ED, Warmuth L, Ritter J, Weber M, Hoffmann M, List M, Kotlarz D, Serr I, Daniel C, Busch DH, Schmidl C, Schumann K. SATB1 is a targetable modulator of JAK-STAT signaling and cytokines in human Treg and Tconv cells. bioRxiv. 2026 Feb 16. doi:10.64898/2026.02.13.705474. PMID: 42051317
Zheng T, Ramanathan K, Ormhoj M, Hansen MR, Halldorsdottir HR, Li H, Munk KK, Rodriguez-Pardo C, Friis RUW, Seder I, Heegaard PMH, Qvortrup K, Abken H, Sun Y, Hadrup SR. Dextran-based T-cell expansion nanoparticles for manufacturing CAR T cells with augmented efficacy. Nat Commun. 2026 Jan 20. 17:1103. doi:10.1038/s41467-025-67868-1. PMID: 41559042
Hirsch ND, Perl M, Holzinger S, Barz C, Enssle S, Johannes W, Conrad A, Unterholzner JJ, Obermeier V, Tschurtschenthaler M, Johannes L, Janssen KP. The Gb3-synthase A4GALT is an epigenetically regulated driver of tumor invasiveness in gastrointestinal cancer. BMC Cancer. 2026 Jan 27. 26:274. doi:10.1186/s12885-026-15600-7. PMID: 41593565
Weidele K, Werno C, Treitschke S, Botteron C, Hoffmann M, Scheitler S, Wohrl L, Czyz Z, Feliciello G, Weber F, Ravikumar Varadarajan A, Warfsmann J, Materna-Reichelt S, Katzer M, Schreieder L, Mohammadi P, Hosseini H, Honarnejad K, Haferkamp S, Werner-Klein M, Klein CA. Micrometastasis-derived models enable drug testing for early-stage, high-risk melanoma patients. EMBO Mol Med. 2026 Jan. 18:297–324. doi:10.1038/s44321-025-00339-8. PMID: 41350774
Lakshmi K, Jutrzenka-Trzebiatowski AV, Loureiro L, Soto KEG, Peter K, Morales JMM, Nirmala SS, Berndt N, Arndt C, Hu Y, Li JW, Peitzsch C, Taubenberger A, Wehner R, Schmitz M, Holig K, Abken H, Bonifacio E, Bornhauser M, Bachmann M, Feldmann A, Fuchs A. Automated GMP-compatible production of universal CAR Tregs for organ-targeted tolerance induction. J Transl Med. 2025 Dec 17. 23:1399. doi:10.1186/s12967-025-07431-0. PMID: 41408297
Lisowski C, Stumpf NE, Jobin K, Klaus D, Eichler M, Baumgart AK, Babyak O, Meissner M, Schroder A, Neubert P, Schmitt V, Michla M, Bozkurt S, Zurkovic J, Hinze D, Liebing J, Eckhardt M, Heuser C, Seep L, Heine A, Becker-Gotot J, Thiele C, Munch C, Becker T, Jantsch J et al. High-salt diet induces immune-independent re-differentiation, metabolic shut down and cell cycle arrest of melanoma. Cell Death Dis. 2025 Dec 20. 17:102. doi:10.1038/s41419-025-08329-x. PMID: 41422056
Magnus CL, Jaber ZH, Hiergeist A, Arnold L, Marchel H, Lamprecht A, Hanses F, Dienemann T, Schneckenpointner R, Lubnow M, Muller T, Lunz D, Hitzenbichler F, Schmid S, Muller M, Poeck H, Graf B, Salzberger B, Gessner A, Schmidt B, Schuster P. SARS-CoV-2 evolution enhances endocytic uptake while preserving TMPRSS2-dependent fusion. Front Immunol. 2025 16:1736891. doi:10.3389/fimmu.2025.1736891. PMID: 41601680
Krieg K, Materna-Reichelt S, Naber T, Rachad FZ, Kauven P, Weller A, Haferkamp U, Wittich A, Zaliani A, Woo MS, Walkenhorst M, Siegmund M, Harberts J, Zierold R, Blick R, Conze C, Muschong P, Miltner D, Friese MA, Mezler M, Siegmund H, Evert K, Krasemann S, Guzvic NS, Klein CA et al. Cortical organoid-derived models of the melanoma brain metastatic niche enable prioritization of cancer-targeting drugs. Cell Rep Methods. 2025 Dec 15. 5:101236. doi:10.1016/j.crmeth.2025.101236. PMID: 41240911
Weber D, Meedt E, Ghimire S, Hiergeist A, Kern MAG, Hopting M, Thiele Orberg E, Shaikh H, Beilhack A, Wolff D, Edinger M, Herr W, Gessner A, Poeck H, Holler E. “The antibiotic paradox” in allogeneic stem cell transplantation. Bone Marrow Transplant. 2025 Nov. 60:1541–1543. doi:10.1038/s41409-025-02706-y. PMID: 40903551