Publications
Research at the Leibniz Institute for Immunology focuses on the development of pioneering immune-cell therapies targeting cancer, autoimmune diseases, and chronic inflammation. While developments in this field are highly relevant within the medical community, they are also of great interest to the wider general public. The LIT has a comprehensive archive of international articles, publications, lectures, and online resources aimed at a variety of audiences. So, whoever you are, if you do not find what you are looking for, please do not hesitate to contact us.
Holzinger A, Weber F, Abken H. The risk of reactivity against healthy tissues: Novel CARs demand testing for overlooked binding properties. Mol Ther. 2025 Jun 4. 33:2328-2329. doi:10.1016/j.ymthe.2024.12.035. PMID: 39818204
Brummer C, Singer K, Renner K, Bruss C, Hellerbrand C, Dorn C, Reichelt-Wurm S, Gronwald W, Pukrop T, Herr W, Banas M, Kreutz M. The spleen-liver axis supports obesity-induced systemic and fatty liver inflammation via MDSC and NKT cell enrichment. Mol Cell Endocrinol. 2025 May 1. 601:112518. doi:10.1016/j.mce.2025.112518. PMID: 40054835
Guetter S, Konig C, Koerkel-Qu H, Markiewicz A, Scheitler S, Katzer M, Berneburg M, Renner P, Cucuruz B, Guttenberger L, Naimer V, Weidele K, Treitschke S, Werno C, Jaser H, Bargmann T, Braun A, Weber F, Evert K, Rochwarger A, Schurch CM, Limm K, Oefner PJ, Rachel R, Baumann F et al. MCSP(+) metastasis founder cells activate immunosuppression early in human melanoma metastatic colonization. Nat Cancer. 2025 May 16. doi:10.1038/s43018-025-00963-w. PMID: 40379833
Kleinschmidt K, Penkivech G, Troeger A, Foell J, Hanafee-Alali T, Leszczak S, Jakob M, Kramer S, Kietz S, Hoffmann P, Behrendt-Bohm C, Kaess C, Brosig A, Offner R, Wolff D, Corbacioglu S. alphass T-cell depleted haploidentical stem cell transplantation for pediatric and young adult patients with transfusion-dependent thalassemia. Bone Marrow Transplant. 2025 May. 60:682-689. doi:10.1038/s41409-025-02546-w. PMID: 40102568
Abken H. CAR T cell therapies in gastrointestinal cancers: current clinical trials and strategies to overcome challenges. Nat Rev Gastroenterol Hepatol. 2025 Apr 14. doi:10.1038/s41575-025-01062-y. PMID: 40229574
Cormican JA, Medfai L, Wawrzyniuk M, Pasen M, Afrache H, Fourny C, Khan S, Gneisse P, Soh WT, Timelli A, Nolfi E, Pannekoek Y, Cope A, Urlaub H, Sijts A, Mishto M, Liepe J. PEPSeek-Mediated Identification of Novel Epitopes From Viral and Bacterial Pathogens and the Impact on Host Cell Immunopeptidomes. Mol Cell Proteomics. 2025 Apr. 24:100937. doi:10.1016/j.mcpro.2025.100937. PMID: 40044041
Heidenreich S, Egger-Heidrich K, Halter JP, Jost L, Stolzel F, Perl M, Denk A, Edinger M, Herr W, Kroger N, Wolff D, Ayuk F, Fante MA. Safety and efficacy of the ROCK-2-inhibitor Belumosudil in cGvHD treatment – a retrospective, German-Swiss multicenter real-world data analysis. Bone Marrow Transplant. 2025 Apr. 60:439-446. doi:10.1038/s41409-024-02507-9. PMID: 39809902
Stuve P, Godoy GJ, Ferreyra FN, Hellriegel F, Boukhallouk F, Kao YS, More TH, Matthies AM, Akimova T, Abraham WR, Kaever V, Schmitz I, Hiller K, Lochner M, Salomon BL, Beier UH, Rehli M, Sparwasser T, Berod L. ACC1 is a dual metabolic-epigenetic regulator of Treg stability and immune tolerance. Mol Metab. 2025 Apr. 94:102111. doi:10.1016/j.molmet.2025.102111. PMID: 39929287
Ewendt F, Drewitz F, Althammer M, Eichler C, Brandsch C, Brey S, Winkler TH, Wilkens MR, St-Arnaud R, Kreutz M, Stangl GI. Vitamin D stimulates Il-15 synthesis in rodent muscle. Biochem Biophys Rep. 2025 Mar. 41:101925. doi:10.1016/j.bbrep.2025.101925. PMID: 40134939