Publications
Research at the Leibniz Institute for Immunology focuses on the development of pioneering immune-cell therapies targeting cancer, autoimmune diseases, and chronic inflammation. While developments in this field are highly relevant within the medical community, they are also of great interest to the wider general public. The LIT has a comprehensive archive of international articles, publications, lectures, and online resources aimed at a variety of audiences. So, whoever you are, if you do not find what you are looking for, please do not hesitate to contact us.
Duque-Afonso J, Finke J, Ngoya M, Galimard JE, Schetelig J, Eder M, Rosler W, Bug G, Neubauer A, Edinger M, Wulf GG, Jindra P, Einsele H, Stelljes M, Selleslag D, Wagner-Drouet EM, Bunjes D, Spyridonidis A, Brissot E, Nagler A, Ciceri F, Mohty M. Comparison of fludarabine/melphalan (FM140) with fludarabine/melphalan/BCNU (FBM110) in patients with relapsed/refractory AML undergoing allogeneic hematopoietic cell transplantation – a registry study on behalf of the EBMT Acute Leukemia Working Party. Bone Marrow Transplant. 2025 Mar. 60:373-379. doi:10.1038/s41409-024-02499-6. PMID: 39702670
Kessel C, Rossig C, Abken H. Weal and woe of interleukin-18 in the T cell therapy of cancer. J Immunother Cancer. 2025 Jan 14. 13doi:10.1136/jitc-2024-010545. PMID: 39809514
Safi S, Krzykalla J, Hoffmann H, Benner A, Bischoff H, Eichhorn M, Kriegsmann M, Poschke I, Stogbauer F, Umansky L, Mogler C, Weichert W, Winter H, Beckhove P, Muley T. Low tumor interleukin-1beta expression predicts a limited effect of adjuvant platinum-based chemotherapy for patients with completely resected lung adenocarcinoma: An identification and validation study. Pulmonology. 2025 Dec 31. 31:2416803. doi:10.1016/j.pulmoe.2024.03.003. PMID: 38614857
Kupke P, Yang Zhou J, Glehr G, Riquelme P, Scheibert L, Adenugba A, Schlitt HJ, Geissler EK, Werner JM, Hutchinson JA. Proteolytic shedding of CD46 from human hepatocytes indicates liver stress. Heliyon. 2024 Dec 15. 10:e40841. doi:10.1016/j.heliyon.2024.e40841. PMID: 39698100
Arslan A, Labuhn S, Sala E, Ringhoffer M, Schetelig J, Schroder T, Bug G, Franke GN, Stelljes M, Dreger P, Zeiser R, Teschner D, Bethge W, Eder M, Edinger M, Amann EM, Neuchel C, Schmid-Moglich A, Schmeller S, Beyersmann J, Schrezenmeier H, Mytilineos J, Kroger N, Furst D. Outcomes of haploidentical transplants with PT-CY vs 10/10 MUD transplants with ATG in Germany. Blood Adv. 2024 Dec 10. 8:6104-6113. doi:10.1182/bloodadvances.2024013719. PMID: 39368803
Brummer C, Singer K, Henrich F, Peter K, Strobl C, Neueder B, Bruss C, Renner K, Pukrop T, Herr W, Aigner M, Kreutz M. The Tumor Metabolite 5′-Deoxy-5’Methylthioadenosine (MTA) Inhibits Maturation and T Cell-Stimulating Capacity of Dendritic Cells. Cells. 2024 Dec 20. 13doi:10.3390/cells13242114. PMID: 39768204
Barden M, Elsenbroich PR, Haas V, Ertelt M, Pervan P, Velas L, Gergely B, Szoor A, Harrer DC, Bezler V, Holzinger A, Friis RUW, Vereb G, Schutz GJ, Schoeder CT, Hombach AA, Abken H. Integrating binding affinity and tonic signaling enables a rational CAR design for augmented T cell function. J Immunother Cancer. 2024 Dec 2. 12doi:10.1136/jitc-2024-010208. PMID: 39622582
Simeth J, Huttl P, Schon M, Nozari Z, Huttner M, Schmidt T, Altenbuchinger M, Spang R. Virtual tissue expression analysis. Bioinformatics. 2024 Nov 28. 40doi:10.1093/bioinformatics/btae709. PMID: 39589902
Galletti G, De Simone G, Mazza EMC, Puccio S, Mezzanotte C, Bi TM, Davydov AN, Metsger M, Scamardella E, Alvisi G, De Paoli F, Zanon V, Scarpa A, Camisa B, Colombo FS, Anselmo A, Peano C, Polletti S, Mavilio D, Gattinoni L, Boi SK, Youngblood BA, Jones RE, Baird DM, Gostick E et al. Two subsets of stem-like CD8(+) memory T cell progenitors with distinct fate commitments in humans. Nat Immunol. 2020 Dec. 21:1552-1562. doi:10.1038/s41590-020-0791-5. PMID: 33046887
Denk A, Mittermaier C, Weber D, Fante M, Gunes S, Edinger M, Herr W, Wolff D. Efficacy and safety of ruxolitinib in the treatment of chronic graft-versus-host disease: a retrospective analysis. Ann Hematol. 2024 Sep. 103:3755-3764. doi:10.1007/s00277-024-05697-w. PMID: 38916742