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CAR T-cells targeting FLT3 have potent activity against FLT3-ITD+ AML and act synergistically with the FLT3-inhibitor crenolanib

Article Details

  • Authors

    • Prof. Simone Thomas

    • Prof. Simone Thomas

  • Date Published

    August 31, 2018

Jetani H, García Cadenas I, Nerreter T, Thomas S, Rydzek J, Briones Meijide J, Bonig H, Herr W, Sierra J, Einsele H, Hudecek M. CAR T-cells targeting FLT3 have potent activity against FLT3-ITD+ AML and act synergistically with the FLT3-inhibitor crenolanib. Leukemia 2018; 32(5):1168. doi: 10.1038/s41375-018-0009-0. PMID: 29472720