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Cortical organoid-derived models of the melanoma brain metastatic niche enable prioritization of cancer-targeting drugs

  • Date Published

    December 18, 2025

Krieg K, Materna-Reichelt S, Naber T, Rachad FZ, Kauven P, Weller A, Haferkamp U, Wittich A, Zaliani A, Woo MS, Walkenhorst M, Siegmund M, Harberts J, Zierold R, Blick R, Conze C, Muschong P, Miltner D, Friese MA, Mezler M, Siegmund H, Evert K, Krasemann S, Guzvic NS, Klein CA et al. Cortical organoid-derived models of the melanoma brain metastatic niche enable prioritization of cancer-targeting drugs. Cell Rep Methods. 2025 Dec 15. 5:101236. doi:10.1016/j.crmeth.2025.101236. PMID: 41240911