CRISPR-Cas9 screen reveals that inhibition of enhancer of zeste homolog 2 sensitizes malignant T cells to dimethyl-fumarate-induced cell death

Date Published

August 28, 2025

Teubner JP, Tumen D, Kandulski A, Heumann P, Mester P, Aschenbrenner E, Pollinger K, Gunckel M, Volz B, Hein T, Beltzig PL, Tengler L, Voll F, Kreutz M, Kunst C, Nicolay JP, Muller M, Gulow K. CRISPR-Cas9 screen reveals that inhibition of enhancer of zeste homolog 2 sensitizes malignant T cells to dimethyl-fumarate-induced cell death. FEBS J. 2025 Aug 1. doi:10.1111/febs.70208. PMID: 40748748