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Lactic acid promotes an MDSC-like phenotype via HIF1alpha stabilization with impact on prognosis in renal cell carcinoma

  • Date Published

    February 18, 2026

Babl N, Voll F, Martowicz A, Bruss C, Maddaloni M, Schmidl C, Rehli M, Loipfinger S, Strieder N, Gebhard C, Hoffmann P, Singh SM, Sala-Hojman A, Ferretti R, Matos C, Simon M, Brummer C, Schnell A, Hofbauer J, Decking SM, Hau P, Vollmann-Zwerenz A, Dettmer K, Oefner PJ, Althammer M et al. Lactic acid promotes an MDSC-like phenotype via HIF1alpha stabilization with impact on prognosis in renal cell carcinoma. Cancer Lett. 2026 Feb 28. 639:218209. doi:10.1016/j.canlet.2025.218209. PMID: 41371433