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Targeting TGFbeta-activated kinase-1 activation in microglia reduces CAR T immune effector cell-associated neurotoxicity syndrome

  • Date Published

    August 1, 2024

Vinnakota JM, Biavasco F, Schwabenland M, Chhatbar C, Adams RC, Erny D, Duquesne S, El Khawanky N, Schmidt D, Fetsch V, Zahringer A, Salie H, Athanassopoulos D, Braun LM, Javorniczky NR, Ho J, Kierdorf K, Marks R, Wasch R, Simonetta F, Andrieux G, Pfeifer D, Monaco G, Capitini C, Fry TJ et al. Targeting TGFbeta-activated kinase-1 activation in microglia reduces CAR T immune effector cell-associated neurotoxicity syndrome. Nat Cancer. 2024 Aug. 5:1227-1249. doi:10.1038/s43018-024-00764-7. PMID: 38741011