Mutations in the STAG2 Protein and the Associated Spatial Alteration of DNA Structure Can Cause Leukemia
13.08.2024Researchers at the Leibniz Institute for Immunotherapy (LIT) studied hundreds of patients with acute myeloid leukemia (AML). They discovered that specific mutations in the STAG2 protein cause altered DNA folding in the cell nucleus, thereby contributing to the development of AML.